A child with hepatic failure received volume replacement.

APT of 14 seconds and PTT of 40 secondsare at the upper limit of normal, and the patient hashepatic failure, which can lead tocoagulopathy. Prior to liver biopsy—a high-risk procedure forbleeding—FFP is administered to replace all clotting factorsand reduce bleeding risk.

“Patients with liver dysfunction undergoing procedures should receive FFP if coagulopathy is present, as it replaces multiple clotting factors synthesized in the liver.”

(Referenced from CCRN Pediatric – Direct Care: Hematology, Coagulation and Transfusion Support)