Which of the following should be included in theadministration instructionsforalendronate?

Comprehensive and Detailed Step-by-Step Explanation:

Alendronate (Fosamax)is abisphosphonateused forosteoporosis. Itprevents bone lossbut can cause severeesophageal irritation and ulcersif not taken correctly.

Correct Administration Instructions for Alendronate:

Take on an empty stomach with a full glass of water (at least 8 oz).

Remain upright (sitting or standing) for at least 30 minutesto prevent esophageal irritation.

Do NOT take with food, milk, or calcium supplementsas they reduce absorption.

????Explanation of Answer Choices:✅A. Do not lie down for at least 30 minutes→Correct.This preventsesophageal irritation and ulcers.❌B. Take with food or milk→ Incorrect.Calcium inhibits alendronate absorption.❌C. May cause drowsiness→ Incorrect.Alendronate does not cause drowsiness.❌D. If a dose is missed, take 2 doses the next day→ Incorrect.Double-dosing increases the risk of side effects.

????Reference:

FDA Drug Labeling for Alendronate

American Association of Clinical Endocrinologists (AACE) Osteoporosis Guidelines

PTCB Exam: Patient Administration Instructions