An administrator receives complaints that non-persistent VDI sessions for an entire department have seen a...

Comprehensive and Detailed Explanation From Exact Extract of Nutanix End User Computing documents:

According to Nutanix VDI Troubleshooting and Performance Tuning best practices:

Symptom Analysis: "Sluggish mouse and keyboard response" is a classic symptom of high CPU contention or high Latency on the host or VM. Since the environment was previously stable ("No additional virtual desktops added") and the change was "dramatic," it points to a new process consuming resources unexpectedly.

The "Agent" Factor: In non-persistent VDI environments, a common cause for sudden performance degradation affecting an "entire department" is an Antivirus or Security Agent running a scheduled scan or a signature update simultaneously across all clones. This creates a "storm" of IOPS and CPU usage (often called an AV storm), starving the user sessions of the resources needed for basic input processing (mouse/keyboard).

Why not others?

Unoptimized master image (B): This would cause poor performance from day one, not a "dramatic change" after 60 days of stability.

Legacy drivers (C): Drivers do not degrade suddenly; they would cause issues from the time of installation.

Over-provisioning (D): This usually results in gradual degradation as user concurrency increases, not a sudden cliff-edge drop in performance if user counts haven't changed.