Pregnant women with diabetes often have problems related to the effectiveness of insulin in controlling...

(A) There is a rise in glomerular filtration rate in the kidneys in conjunction with decreased tubular glucose reabsorption, resulting in glycosuria. (B) Insulin is inhibited by increased levels of estrogen. (C) Insulin is inhibited by increased levels of progesterone. (D) Human placental lactogen levels increase later in pregnancy. This hormonal antagonist reduces insulin’s effectiveness, stimulates lipolysis, and increases the circulation of free fatty acids.