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You are evaluating a 75-year-old man with recently diagnosed prostate cancer and 2 painful metastases...

You are evaluating a 75-year-old man with recently diagnosed prostate cancer and 2 painful metastases of the lumbar spine. Which one of the following therapeutic options is the most appropriate?

A.

Intrathecal steroid injection

B.

Surgical castration (orchidectomy)

C.

Oral anti-androgen plus gonadotropin-releasing hormone agonist

D.

Fentanyl patch and breakthrough opioids

E.

Palliative radiotherapy to the lumbar spine

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