A 59-year-old woman comes to the office because her 48-year-old sister was recently diagnosed with...

For women aged 25–69 years who have had adequate negative screening, the recommendation is to repeat cervical cytology (Pap test) every 3 years, regardless of family history. Cervical cancer is caused primarily by HPV infection, not hereditary genetics. Family history does not alter the screening interval.

Toronto Notes 2023 – Gynecology, Cervical Cancer Screening Section:

“Routine screening with Pap test is recommended every 3 years in women aged 25–69 who have had three consecutive negative tests. Family history of cervical cancer does not modify the screening interval.”

MCCQE1 Objectives – Obstetrics and Gynecology > Cancer Screening:

“Candidates must apply population-based cervical cancer screening guidelines. Family history is not a risk modifier for screening frequency in cervical cancer.”

Options A and B are inappropriate as they increase screening frequency without indication. HPV testing (D) or colposcopy (E) are not recommended without abnormal cytology.

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