The difference between GitHub Desktop and github.

GitHub Desktop is a standalone application that provides a graphical user interface (GUI) for interacting with GitHub repositories, as opposed to the command-line or web-based interfaces available on github.com.

Graphical User Interface:

Option D is correct because GitHub Desktop offers a GUI, making it easier for users to manage repositories, perform commits, and handle other Git-related tasks without needing to use the command line.

Incorrect Options:

Option A is partially correct in that GitHub Desktop is a standalone application, but the key difference is the GUI.

Option B is incorrect because GitHub Desktop does not specifically enable integration with office suite applications.

Option C is incorrect because GitHub Desktop is available on both Windows and macOS.

Option E is incorrect because GitHub Desktop is not a self-hosted version of GitHub; it is a client application for accessing GitHub repositories.