If the total body clearance of a drug is 200 mL/min in a normal healthy...

NABP FPGEE Question Answer

If the total body clearance of a drug is 200 mL/min in a normal healthy adult and the renal clearance is 10 mL/min then one may assume that:

the drug is extensively metabolized.

greater than normal drug accumulation would occur in patients with moderate renal failure.

entero-hepatic recycling is significant.

the drug is not bound to plasma proteins.

the drug is concentrated in adipose tissue.

FPGEE PDF/Engine

Get 75% Discount on All Products, Use Coupon: "ac75sure"