Sentinel events are most often the result of variations in:

Sentinel events usually result from process failures—breakdowns or variations in how care is delivered, such as communication failures, procedural lapses, or system errors (The Joint Commission, Sentinel Event Policy, 2024; AHRQ, Patient Safety and Quality, 2023).

While staffing and competence impact care, process issues are more commonly root causes.

Structure refers to physical or organizational infrastructure, less commonly the direct cause.