The infection preventionist understands that the heating, ventilation and air conditioning (HVAC) systems in the...

Patients in pediatric oncology units are highly immunocompromised, making them particularly susceptible to opportunistic fungal infections such asAspergillusspp. HVAC systems, especially if improperly maintained or contaminated, can disseminate fungal spores into patient care areas.

According to theAPIC Text (Chapter 116 – HVAC Systems), fungal spores such asAspergilluscan be transmitted via HVAC systems. These infections have been linked to contaminated air ducts, faulty air filters, and construction-related air disturbances. Outbreaks of aspergillosis are frequently associated with construction near patient care areas and are particularly dangerous for immunocompromised patients, including pediatric oncology patients.

Additional data fromAPIC Text (Chapter 45 – Infection Prevention in Oncology Patients)reinforces thatAspergillusspp. infections in oncology and immunocompromised patients are primarily airborne and are most often disseminated via HVAC systems.

Incorrect answer rationale:

A. MRSA– Typically spread via direct contact, not HVAC.

B. Norovirus– Spread via fecal-oral route and contaminated surfaces, not airborne HVAC.

D.Clostridioides difficile– Spread via contact with spores on surfaces, not through the air.