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The combination of complement C4, C2 and C3 that binds to the antigen-antibody complex in...

The combination of complement C4, C2 and C3 that binds to the antigen-antibody complex in the initial reaction step in the classical pathway of complement activation is called the activation unit.

Which of the following is the "activation unit" in the classical complement pathway?

A.

C1

B.

C2

C.

C4, C2, C3

D.

C5, C6, C7, C8, C9

E.

C1, C2, C9

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