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While reviewing reports of data completion, the sponsor notices low retention rates at many participating...

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While reviewing reports of data completion, the sponsor notices low retention rates at many participating sites. What is an appropriate FIRST action for the sponsor to take?

A.

Interview participants who have dropped out.

B.

Require participants to provide documented reason for withdrawal.

C.

Submit revised ICFs to the IRB/IEC with increased compensation for participants.

D.

Meet with the site staff to understand their workflows and to review retention strategies.

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