Which cause of transudative pleural effusion is most common?
A.
Congestive heart failure
B.
Pulmonary emboli
C.
Lymphoma
D.
Empyema
The Answer Is:
A
This question includes an explanation.
Explanation:
Transudative pleural effusions result from imbalances in hydrostatic and oncotic pressures, most commonly caused by congestive heart failure (CHF). In CHF, elevated hydrostatic pressure in the pulmonary capillaries leads to fluid leakage into the pleural space without significant protein or cellular content (hence, transudate). Exudative effusions (associated with infections, malignancy, and inflammation) are more often seen with pulmonary emboli, lymphoma, or empyema.
According to Light’s criteria (which differentiates transudates from exudates):
"Congestive heart failure remains the leading cause of transudative pleural effusions." (Light RW. Pleural Diseases, 6th ed.).
[Reference:, Light RW. Pleural Diseases. 6th ed. Lippincott Williams & Wilkins, 2013., American Thoracic Society Guidelines for Diagnosis and Management of Pleural Effusion, 2019., —]
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