A large pharmaceutical company using a new AI solution to develop treatment regimens is concerned...

AAISM materials identify human-in-the-loop governance as the most effective safeguard against risks such as hallucinations in AI systems used in high-stakes domains like healthcare. By ensuring that human experts validate outputs before they influence patient treatment decisions, organizations preserve accountability, safety, and accuracy. Penetration testing is a cybersecurity measure, not relevant to hallucination risk. AI impact analysis helps evaluate systemic effects but does not directly prevent faulty outputs. Data validation improves input quality but cannot fully prevent generative hallucinations. The key safeguard is human-in-the-loop oversight.